Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | LTK | P29376 | 1/20 | 0.52 |
| ▸ | GRK5 | P34947 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | PRKX | P51817 | 1/20 | 0.52 |
| ▸ | NEK2 | P51955 | 1/20 | 0.52 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.52 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036286 | 0.87 | CHEK1 (0.67) | SLC22A6SLC22A8CHEK1DAPK3PRKD3 | |
| SCHEMBL7512841 | 0.82 | SLC22A6 (0.59) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 | |
| SCHEMBL8894473 | 0.81 | CHEK1 (0.76) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8553507 | 0.79 | CHEK1 (0.53) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8557524 | 0.78 | CHEK1 (0.51) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL9059384 | 0.78 | CHEK1 (0.51) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL8554275 | 0.77 | CHEK1 (0.48) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL7811014 | 0.76 | SLC22A6 (0.77) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 | |
| SCHEMBL8798774 | 0.75 | CHEK1 (0.47) | SLC22A6SLC22A8CHEK1DAPK3PRKD3 | |
| SCHEMBL8191650 | 0.75 | SLC22A6 (0.61) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010572-A1 | NEW HETEROCYCLIC SUBSTITUTED IMIDAZOLOQUINOXALINONES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-11 | — | — | WO | disclosed |