Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12667145 | 0.83 | BRD4 (0.62) | BRD4GAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3140082 | 0.83 | BRD4 (0.62) | BRD4GAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL12667147 | 0.83 | BRD4 (0.62) | BRD4GAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14636509 | 0.81 | POLB (0.50) | GAAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL20481270 | 0.80 | BRD4 (0.43) | BRD4GAAALDH1A1NPSR1TP53 | |
| SCHEMBL6869169 | 0.80 | BRD4 (0.50) | BRD4GAAALDH1A1NPSR1TP53 | |
| SCHEMBL14636507 | 0.78 | BRD4 (0.69) | BRD4GAAALDH1A1NPSR1TP53 | |
| SCHEMBL16758839 | 0.77 | SMN1; SMN2 (0.42) | BRD4ALDH1A1NPSR1SMN1; SMN2HSP90AA1 | |
| SCHEMBL14990930 | 0.75 | BRD4 (0.69) | BRD4GAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL11997296 | 0.74 | BRD4 (0.63) | BRD4GAAALDH1A1SMN1; SMN2FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002504-A1 | 6-BIPHENYLOXYMETHYL-4-CARBOXY-2-PIPERIDINONES, DRUGS CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |