Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511684 | 0.86 | BRD4 (0.60) | BRD4SMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL9057201 | 0.80 | BRD4 (0.50) | BRD4SMN1; SMN2FKBP1AHPGDMAPT | |
| SCHEMBL6873102 | 0.78 | BRD4 (0.47) | BRD4RAB9A | |
| SCHEMBL5048047 | 0.78 | FKBP1A (0.40) | BRD4SMN1; SMN2FKBP1AL3MBTL1HPGD | |
| SCHEMBL6873311 | 0.75 | ALDH1A1 (0.47) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL15042048 | 0.75 | BRD4 (0.70) | BRD4SMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL15042122 | 0.75 | BRD4 (0.60) | BRD4SMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL16059156 | 0.75 | APEX1 (0.36) | L3MBTL1POLB | |
| SCHEMBL14636507 | 0.75 | BRD4 (0.69) | BRD4SMN1; SMN2TP53ALDH1A1NPSR1 | |
| SCHEMBL16058256 | 0.74 | L3MBTL1 (0.36) | BRD4L3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395560-A1 | 2-OXO-PIPERIDINYL- AND 2-OXO-AZEPANYL ALKANOIC ACID DERIVATIV ES FOR THE TREATMENT OF EPILEPSY AND OTHER NEUROLOGICAL DISORDERS | UCB, S.A. (BE) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094787-A1 | 2-OXO-PIPERIDINYL- AND 2-OXO-AZEPANYL ALKANOIC ACID DERIVATIV ES FOR THE TREATMENT OF EPILEPSY AND OTHER NEUROLOGICAL DISORDERS | UCB, S.A. (BE) | 2002-11-28 | — | — | WO | disclosed |