Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834900 | 0.84 | ALDH1A1 (0.51) | HSD17B10PKMMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10423673 | 0.84 | ALDH1A1 (0.51) | HSD17B10PKMMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9734549 | 0.81 | CA1 (0.48) | HSD17B10ALDH1A1HIF1AADRB2ADRB1 | |
| SCHEMBL9780181 | 0.80 | KCNA5 (0.38) | ALDH1A1HTTGAAMAPTMEN1 | |
| SCHEMBL9733728 | 0.80 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL28638974 | 0.80 | ALDH1A1 (0.60) | HSD17B10PKMMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8535929 | 0.79 | KCNA5 (0.49) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9735344 | 0.77 | PLK1 (0.45) | SMN1; SMN2ALDH1A1HTTGAAMAPT | |
| SCHEMBL15047897 | 0.77 | SMN1; SMN2 (0.57) | HSD17B10PKMMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11235456 | 0.75 | SMN1; SMN2 (0.55) | HSD17B10PKMMAPK1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8151350-A | — | — | None | — | — | JP | disclosed |
| CN-106518850-A | Chemical synthesis method of Pimobendan | 青岛农业大学 | 2017-03-22 | — | — | CN | disclosed |
| JP-H08151350-A | PRODUCTION OF OPTICALLY ACTIVE SUBSTITUTED BUTYRIC ACID ESTER | MITSUBISHI RAYON CO LTD | 1996-06-11 | — | — | JP | disclosed |