Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ESRRB | O95718 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734549 | 0.84 | CA1 (0.48) | KCNA5KMT2ATSHRESRRBALDH1A1 | |
| SCHEMBL6512379 | 0.83 | KCNA5 (0.47) | KCNA5KMT2AUSP2TSHRPGR | |
| SCHEMBL11732434 | 0.83 | KMT2A (0.53) | KMT2AUSP2TSHRPGRADRA2A | |
| SCHEMBL9733728 | 0.83 | ALDH1A1 (0.51) | KMT2AALDH1A1LMNAMEN1TDP1 | |
| SCHEMBL9780181 | 0.83 | KCNA5 (0.38) | KCNA5KMT2AUSP2ADRA2BESRRB | |
| SCHEMBL8594326 | 0.83 | MAOB (0.57) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL22076551 | 0.82 | KMT2A (0.49) | KCNA5KMT2ATSHRPGRADRA2A | |
| SCHEMBL10696373 | 0.81 | CES2 (0.54) | KMT2ATSHRALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL8823315 | 0.81 | PGR (0.52) | KMT2ATSHRPGRADRA2AADRA2B | |
| SCHEMBL135357 | 0.81 | PGR (0.52) | KMT2ATSHRPGRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216522-A | Therapeutic agent for diabetes | JAPAN TOBACCO INC (JP) | 1999-05-12 | — | — | CN | disclosed |
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |