Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.80 |
| ▸ | RAB9A | P51151 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Linuron SCHEMBL9419428 | 0.96 | PKM (0.74) | PKMRAB9AKMT2AMEN1APEX1 | |
| Linuron SCHEMBL56566 | 0.94 | KMT2A (0.76) | PKMRAB9AKMT2AMEN1APEX1 | |
| Linuron SCHEMBL8406948 | 0.94 | KMT2A (0.76) | PKMRAB9AKMT2AMEN1APEX1 | |
| Linuron SCHEMBL27260336 | 0.94 | KMT2A (0.76) | PKMRAB9AKMT2AMEN1APEX1 | |
| Chloroxuron SCHEMBL8602342 | 0.91 | PKM (0.67) | PKMRAB9AKMT2AMEN1APEX1 | |
| Linuron SCHEMBL28168150 | 0.91 | KMT2A (0.72) | PKMRAB9AKMT2AMEN1APEX1 | |
| Linuron SCHEMBL9057322 | 0.90 | APEX1 (0.79) | PKMRAB9AKMT2AMEN1APEX1 | |
| Monolinuron SCHEMBL1701381 | 0.89 | RAB9A (1.00) | PKMRAB9AKMT2AMEN1NPC1 | |
| Monolinuron SCHEMBL65568 | 0.89 | RAB9A (1.00) | PKMRAB9AKMT2AMEN1NPC1 | |
| Linuron SCHEMBL11414948 | 0.87 | KMT2A (0.67) | PKMRAB9AKMT2AMEN1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413267-B1 | Water-dispersible granules | HOECHST SCHERING AGREVO GMBH (DE) | 1997-11-12 | — | — | EP | disclosed |
| US-5648477-A | Genetically engineered plant cells and plants exhibiting resistance to glutamine synthetase inhibitors, DNA fragments and recombinants for use in the production of said cells and plants | PLANT GENETIC SYSTEMS, N.V. (BE) | 1997-07-15 | — | — | US | disclosed |
| US-3954442-A | 4-PHENOXY-PHENOXY-ALKANE-CARBOXYLIC ACIDS AND DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |