Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057077 | 0.92 | CA2 (0.44) | CA2CA4CA12CA1CA9 | |
| SCHEMBL9058101 | 0.88 | CA2 (0.33) | CA2CA4CA12CA1CA9 | |
| SCHEMBL9058320 | 0.83 | CA2 (0.42) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL8950276 | 0.78 | CA2 (0.53) | CA2CA4CA12CA1CA9 | |
| SCHEMBL9057841 | 0.77 | CA2 (0.36) | CA2 | |
| SCHEMBL9058810 | 0.77 | CA2 (0.32) | CA2 | |
| SCHEMBL9058028 | 0.77 | CA2 (0.59) | CA2CA4CA12CA1CA9 | |
| SCHEMBL9057333 | 0.75 | CA2 (0.47) | CA2CA4CA12CA1CA9 | |
| SCHEMBL8950227 | 0.73 | CA2 (0.65) | CA2CA4CA12CA1CA9 | |
| SCHEMBL9058135 | 0.71 | CA2 (0.45) | CA2CA4CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022099-A1 | OPHTHALMIC COMPOSITIONS FOR TREATING GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-25 | — | — | WO | disclosed |
| WO-1995019981-A1 | THIENOTHIAZINE SULFONAMIDE DERIVATIVES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS CARBONIC ANHYDRASE INHIBITORS | ALCON LABORATORIES, INC. (US) | 1995-07-27 | — | — | WO | disclosed |