Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057077 | 0.88 | CA2 (0.44) | CA2CA4 | |
| SCHEMBL9057426 | 0.83 | CA2 (0.37) | CA2CA4 | |
| SCHEMBL9058101 | 0.82 | CA2 (0.33) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL8950237 | 0.79 | CA2 (0.62) | CA2CA4 | |
| SCHEMBL9058131 | 0.77 | CA2 (0.67) | CA2CA4 | |
| SCHEMBL9058810 | 0.76 | CA2 (0.32) | CA2 | |
| SCHEMBL9057841 | 0.76 | CA2 (0.36) | CA2 | |
| SCHEMBL9057333 | 0.73 | CA2 (0.47) | CA2CA4ALOX15 | |
| SCHEMBL677635 | 0.71 | CA2 (0.51) | CA2CA4 | |
| SCHEMBL9058837 | 0.66 | CA2 (0.68) | CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022099-A1 | OPHTHALMIC COMPOSITIONS FOR TREATING GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-25 | — | — | WO | disclosed |
| WO-1995019981-A1 | THIENOTHIAZINE SULFONAMIDE DERIVATIVES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS CARBONIC ANHYDRASE INHIBITORS | ALCON LABORATORIES, INC. (US) | 1995-07-27 | — | — | WO | disclosed |