Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343533 | 0.76 | NR4A1 (0.50) | ALDH1A1HSD17B10HPGDCYP1A2KMT2A | |
| SCHEMBL28272111 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HPGDCYP1A2KMT2A | |
| SCHEMBL3341373 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HPGDCYP1A2KMT2A | |
| SCHEMBL2837799 | 0.74 | ALDH1A1 (0.55) | ALDH1A1HSD17B10HPGDCYP1A2KMT2A | |
| Pyrene SCHEMBL21599111 | 0.73 | ALDH1A1 (0.69) | ALDH1A1HSD17B10HPGDCYP1A2KMT2A | |
| SCHEMBL242958 | 0.72 | HSD17B10 (0.64) | ALDH1A1HSD17B10HPGDCYP1A2KMT2A | |
| SCHEMBL29350533 | 0.72 | HSD17B10 (0.64) | ALDH1A1HSD17B10HPGDCYP1A2KMT2A | |
| SCHEMBL28872577 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HPGDCYP1A2KMT2A | |
| SCHEMBL2086850 | 0.71 | CYP1A2 (0.47) | ALDH1A1HSD17B10HPGDCYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL8600808 | 0.71 | HSD17B10 (0.62) | ALDH1A1HSD17B10HPGDCYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996001627-A1 | USE OF SWINHOLIDE A FOR SEVERING AND DEPOLYMERIZING ACTIN | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH ANS HUMA SERVICES (US) | 1996-01-25 | — | — | WO | disclosed |