SCHEMBL2086850

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2837799	0.85	ALDH1A1 (0.55)	CYP1A2ERBB2FYNMAOAACHE
	SCHEMBL2290967	0.78	HPRT1 (0.54)	CYP1A2ERBB2FYNMAOAACHE
	SCHEMBL69928	0.77	CYP1A2 (0.50)	CYP1A2MAOAALDH1A1HPGDHSD17B10
	SCHEMBL7751770	0.77	CYP1A2 (0.50)	CYP1A2MAOAALDH1A1HPGDHSD17B10
	SCHEMBL28872577	0.72	ALDH1A1 (0.50)	CYP1A2ERBB2FYNMAOAACHE
	SCHEMBL28272111	0.72	ALDH1A1 (0.50)	CYP1A2ERBB2FYNMAOAACHE
	SCHEMBL3341373	0.72	ALDH1A1 (0.50)	CYP1A2ERBB2FYNMAOAACHE
	SCHEMBL348429	0.72	SIGMAR1 (0.41)	CYP1A2ERBB2FYNMAOAACHE
	Pyrene SCHEMBL27863015	0.71	ALDH1A1 (0.67)	CYP1A2ERBB2FYNMAOAACHE
	SCHEMBL9057553	0.71	ALDH1A1 (0.47)	CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.