Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057491 | 0.82 | PDE3B (0.40) | KDM4EPDE3BPDE3APOLBALDH1A1 | |
| SCHEMBL9056192 | 0.82 | PDE3B (0.40) | KDM4EPDE3BPDE3APOLBALDH1A1 | |
| SCHEMBL9039803 | 0.80 | AGTR1 (0.53) | — | |
| SCHEMBL9056251 | 0.79 | PDE3B (0.42) | KDM4EGAAPDE3BPDE3APOLB | |
| SCHEMBL9058024 | 0.79 | PDE3B (0.42) | KDM4EGAAPDE3BPDE3APOLB | |
| SCHEMBL9043115 | 0.77 | AGTR1 (0.41) | — | |
| SCHEMBL9057832 | 0.75 | PDE3B (0.41) | KDM4EPDE3BPDE3APOLBALDH1A1 | |
| SCHEMBL9056202 | 0.75 | SMN1; SMN2 (0.36) | KDM4EGAAPDE3BPDE3APOLB | |
| SCHEMBL9056751 | 0.74 | PDE3B (0.40) | CASP3PDE3BPDE3APOLBALDH1A1 | |
| SCHEMBL9056321 | 0.74 | POLB (0.39) | KDM4EGAAPDE3BPDE3APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |