Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057832 | 0.94 | PDE3B (0.41) | PDE3BPDE3APOLBL3MBTL1ALOX5 | |
| SCHEMBL9057491 | 0.84 | PDE3B (0.40) | PDE3BPDE3APOLBL3MBTL1ALOX5 | |
| SCHEMBL9057724 | 0.82 | CASP3 (0.44) | PDE3BPDE3APOLBALOX5MAPT | |
| SCHEMBL9056689 | 0.78 | ALOX5 (0.36) | PDE3BPDE3AALOX5MAPTSMN1; SMN2 | |
| SCHEMBL9056202 | 0.76 | SMN1; SMN2 (0.36) | PDE3BPDE3APOLBL3MBTL1MAPT | |
| SCHEMBL9056168 | 0.76 | PDE3B (0.40) | PDE3BPDE3APOLBL3MBTL1ALOX5 | |
| SCHEMBL9056321 | 0.76 | POLB (0.39) | PDE3BPDE3APOLBL3MBTL1MAPT | |
| SCHEMBL9056751 | 0.76 | PDE3B (0.40) | PDE3BPDE3APOLBL3MBTL1ALOX5 | |
| SCHEMBL9056909 | 0.75 | SMN1; SMN2 (0.35) | PDE3BPDE3APOLBL3MBTL1MAPT | |
| SCHEMBL9056166 | 0.75 | PTPN1 (0.41) | PDE3BPDE3APOLBL3MBTL1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |