Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.62 |
| ▸ | DRD2 | P14416 | 14/20 | 0.62 |
| ▸ | HTR2A | P28223 | 4/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885700 | 0.91 | HTR1A (0.59) | HTR1ADRD2HTR2ADRD1DRD3 | |
| SCHEMBL8693479 | 0.91 | HTR1A (0.59) | HTR1ADRD2HTR2ADRD1DRD3 | |
| SCHEMBL9057855 | 0.87 | HTR1A (0.59) | HTR1ADRD2HTR2ADRD1DRD3 | |
| SCHEMBL8695028 | 0.85 | HTR1A (0.58) | HTR1ADRD2HTR2ASLC6A4 | |
| SCHEMBL8872506 | 0.85 | HTR1A (0.58) | HTR1ADRD2HTR2ASLC6A4 | |
| SCHEMBL7887609 | 0.80 | HTR1A (0.55) | HTR1ADRD2HTR2ASLC6A4 | |
| SCHEMBL8698666 | 0.80 | HTR1A (0.55) | HTR1ADRD2HTR2ASLC6A4 | |
| SCHEMBL7885650 | 0.80 | HTR1A (0.59) | HTR1ADRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8695915 | 0.80 | HTR1A (0.59) | HTR1ADRD2HTR2ADRD3SLC6A4 | |
| Hydrochloric Acid SCHEMBL11010285 | 0.78 | KDM4E (0.53) | HTR1ADRD2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022290-A1 | COMPOUNDS HAVING EFFECTS ON SEROTONIN-RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |