Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 0.59 |
| ▸ | DRD2 | P14416 | 11/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885700 | 1.00 | HTR1A (0.59) | HTR1ADRD2SLC6A4HTR2ADRD1 | |
| SCHEMBL8695028 | 0.94 | HTR1A (0.58) | HTR1ADRD2SLC6A4HTR2AADRA1D | |
| SCHEMBL8872506 | 0.94 | HTR1A (0.58) | HTR1ADRD2SLC6A4HTR2AADRA1D | |
| SCHEMBL9057865 | 0.91 | HTR1A (0.62) | HTR1ADRD2SLC6A4HTR2ADRD1 | |
| SCHEMBL7885650 | 0.89 | HTR1A (0.59) | HTR1ADRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL8695915 | 0.89 | HTR1A (0.59) | HTR1ADRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL8698666 | 0.89 | HTR1A (0.55) | HTR1ADRD2SLC6A4HTR2AADRA1D | |
| SCHEMBL7887609 | 0.89 | HTR1A (0.55) | HTR1ADRD2SLC6A4HTR2AADRA1D | |
| SCHEMBL7883019 | 0.87 | HTR1A (0.60) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL8690982 | 0.85 | HTR1A (0.60) | HTR1ASLC6A4ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789402-A | Compounds having effects on serotonin-related systems | ELI LILLY COMPANY (US) | 1998-08-04 | — | — | US | disclosed |
| US-5741789-A | HETERO-OXY ALKANAMINES | ELI LILLY AND COMPANY (US) | 1998-04-21 | — | — | US | disclosed |