Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | HTR5A | P47898 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | HRH1 | P35367 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400087 | 0.91 | LTA4H (0.65) | LMNAMEN1HTTKMT2AHRH3 | |
| SCHEMBL6655573 | 0.85 | KMT2A (0.60) | LMNAMEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL3886790 | 0.84 | KDM4E (0.59) | HRH3ALDH1A1HTR1ADRD2HTR2A | |
| SCHEMBL6649042 | 0.84 | HRH3 (0.52) | LMNAMEN1HTTKMT2AHRH3 | |
| SCHEMBL6651979 | 0.83 | MEN1 (0.52) | LMNAMEN1HTTKMT2AHRH3 | |
| SCHEMBL490523 | 0.83 | MEN1 (1.00) | LMNAMEN1HTTKMT2AHRH3 | |
| SCHEMBL1728918 | 0.82 | USP2 (0.78) | LMNAMEN1HTTKMT2AHRH3 | |
| SCHEMBL7389910 | 0.81 | LMNA (0.74) | LMNAMEN1HTTKMT2AHRH3 | |
| SCHEMBL7403863 | 0.81 | HRH3 (1.00) | LMNAMEN1HTTKMT2AHRH3 | |
| SCHEMBL5856197 | 0.81 | MEN1 (0.97) | LMNAMEN1HTTKMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996012718-A1 | NOUVELLES 2-[1-(φ-PHENOXYALCOYLPIPERIDIN-4-YL)AMINOMETHYLENE]-2H-BENZOFURAN-3-ONES SUBSTITUEES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | disclosed |