Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802237 | 0.92 | MEN1 (0.47) | MEN1KMT2AMCL1ELANEKDM4E | |
| SCHEMBL8390532 | 0.85 | PTGES2 (0.44) | MEN1KMT2AMCL1ELANEKDM4E | |
| SCHEMBL8391236 | 0.84 | MAPT (0.44) | MEN1KMT2AMCL1KDM4ESMN1; SMN2 | |
| SCHEMBL8391206 | 0.84 | MEN1 (0.47) | MEN1KMT2AMCL1ELANEKDM4E | |
| SCHEMBL9057704 | 0.83 | MEN1 (0.42) | MEN1KMT2AMCL1ELANEKDM4E | |
| SCHEMBL9056342 | 0.83 | ELANE (0.42) | MEN1KMT2AELANEKDM4ESMN1; SMN2 | |
| SCHEMBL8803349 | 0.83 | MEN1 (0.50) | MEN1KMT2AMCL1ELANEKDM4E | |
| SCHEMBL8389084 | 0.82 | CCR2 (0.47) | MEN1KMT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL8389290 | 0.82 | MAPT (0.43) | MEN1KMT2ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL8387479 | 0.82 | ELANE (0.44) | MEN1KMT2AMCL1ELANEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |