Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056994 | 0.84 | TSHR (0.34) | NR3C2KCNA3TSHRCYP2D6LMNA | |
| SCHEMBL8013258 | 0.78 | NR3C2 (0.51) | NR3C2KCNA3TSHRCYP2C19GLA | |
| SCHEMBL8808852 | 0.78 | HRH4 (0.35) | HCAR3SMN1; SMN2ALDH1A1 | |
| SCHEMBL11342835 | 0.74 | ESR1 (0.35) | TSHRLMNASMN1; SMN2ALDH1A1TAAR1 | |
| SCHEMBL4973167 | 0.73 | HCAR3 (0.50) | TSHRCYP2D6CYP2C19LMNAHCAR3 | |
| SCHEMBL9056943 | 0.72 | CYP2C19 (0.37) | NR3C2TSHRCYP2C19LMNASMN1; SMN2 | |
| SCHEMBL5106910 | 0.71 | TSHR (0.35) | TSHRCYP2D6CYP2C19LMNAHCAR3 | |
| SCHEMBL27610862 | 0.70 | TSHR (0.38) | TSHRCYP2D6CYP2C19LMNAHCAR3 | |
| SCHEMBL5071266 | 0.70 | PARP1 (0.39) | LMNAHCAR3SMN1; SMN2ALDH1A1IP6K1 | |
| SCHEMBL2058979 | 0.69 | CYP2C19 (0.64) | TSHRCYP2D6CYP2C19LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |