Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23822917 | 0.83 | HIF1A (0.56) | TP53NPC1RAB9AKMT2ATHRB | |
| SCHEMBL27176302 | 0.80 | NPC1 (0.54) | TP53NPC1RAB9AKMT2ATHRB | |
| SCHEMBL1178560 | 0.80 | TP53 (0.53) | TP53NPC1RAB9AKMT2ATHRB | |
| SCHEMBL1178691 | 0.78 | LMNA (0.81) | NPC1RAB9AKMT2AHIF1ASMN1; SMN2 | |
| SCHEMBL1178853 | 0.78 | LMNA (0.55) | TP53NPC1RAB9AKMT2ATHRB | |
| SCHEMBL892395 | 0.77 | SNCA (0.60) | TP53THRB | |
| SCHEMBL11931680 | 0.77 | NPC1 (1.00) | NPC1RAB9AKMT2A | |
| SCHEMBL892967 | 0.77 | CDH1 (0.82) | TP53NPC1RAB9AKMT2ATHRB | |
| SCHEMBL16401825 | 0.77 | CDH1 (0.63) | TP53NPC1RAB9AKMT2ATHRB | |
| SCHEMBL20507305 | 0.76 | HDAC6 (0.82) | TP53NPC1RAB9AKMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8027130-A | — | — | None | — | — | JP | disclosed |
| JP-H0827130-A | NEW 5-SUBSTITUTED ISOXAZOLE-3-CARBOXYAMIDE DERIVATIVE | TEIKOKU HORMONE MFG CO LTD | 1996-01-30 | — | — | JP | disclosed |