Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20851318 | 0.79 | MAPT (0.58) | AAK1CYP3A4ALDH1A1HPGDKDM4E | |
| SCHEMBL7089770 | 0.76 | CYP2C9 (0.43) | AAK1CYP3A4ALDH1A1HPGDMAPT | |
| SCHEMBL10928111 | 0.73 | CHRNA7 (0.40) | ALDH1A1HPGDMAPTLMNAMMP2 | |
| SCHEMBL9057710 | 0.73 | AAK1 (0.49) | AAK1CYP3A4ALDH1A1HPGDKDM4E | |
| SCHEMBL14465630 | 0.72 | HPGD (0.51) | AAK1CYP3A4ALDH1A1HPGDKDM4E | |
| SCHEMBL20851317 | 0.72 | HPGD (0.70) | AAK1CYP3A4ALDH1A1HPGDKDM4E | |
| SCHEMBL14672093 | 0.72 | MAPT (0.57) | AAK1CYP3A4ALDH1A1HPGDKDM4E | |
| SCHEMBL123415 | 0.71 | MAPT (0.55) | ALDH1A1HPGDKDM4EMAPTPOLB | |
| SCHEMBL3685845 | 0.71 | AAK1 (0.46) | AAK1CYP3A4ALDH1A1HPGDKDM4E | |
| SCHEMBL8956858 | 0.70 | SLC1A5 (0.48) | CYP3A4ALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407830-B1 | Polarizer | HOFFMANN LA ROCHE (CH) | 1996-09-25 | — | — | EP | disclosed |