Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23367797 | 0.79 | HIF1A (0.41) | AAK1CYP3A4ALDH1A1HPGDKDM4E | |
| SCHEMBL7900745 | 0.77 | KDM1A (0.46) | MMP2MMP3ALDH1A1HPGDKDM4E | |
| SCHEMBL9924742 | 0.75 | MMP2 (0.61) | MMP2MMP3ALDH1A1HPGDKDM4E | |
| SCHEMBL20851318 | 0.75 | MAPT (0.58) | AAK1CYP3A4ALDH1A1HPGDKDM4E | |
| SCHEMBL10927812 | 0.73 | KDM1A (0.40) | AAK1CYP3A4MMP2MMP3ALDH1A1 | |
| SCHEMBL8956799 | 0.73 | ADRB2 (0.45) | CYP3A4ALDH1A1MAPTTSHRLMNA | |
| SCHEMBL9057992 | 0.73 | AAK1 (0.53) | AAK1CYP3A4MMP2MMP3ALDH1A1 | |
| SCHEMBL7899217 | 0.72 | MAOA (0.48) | MMP2MMP3ALDH1A1HPGDKDM4E | |
| SCHEMBL10928111 | 0.72 | CHRNA7 (0.40) | MMP2MMP3ALDH1A1HPGDMAPT | |
| SCHEMBL10929262 | 0.70 | KDM1A (0.38) | AAK1CYP3A4MMP2MMP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407830-B1 | Polarizer | HOFFMANN LA ROCHE (CH) | 1996-09-25 | — | — | EP | disclosed |