Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | WNT1 | P04628 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.45 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31182034 | 0.80 | PFKFB3 (0.48) | CTSVCTSLCTSBCTSSIRAK1 | |
| SCHEMBL17547081 | 0.80 | PFKFB3 (0.48) | CTSVCTSLCTSBCTSSIRAK1 | |
| SCHEMBL16597444 | 0.79 | TEK (0.47) | CTSVCTSLCTSBCTSSIRAK1 | |
| SCHEMBL18492830 | 0.79 | LOXL2 (0.51) | CTSVCTSLCTSBCTSSIRAK1 | |
| SCHEMBL16675749 | 0.79 | PRKCI (0.51) | CTSVCTSLCTSBCTSSIRAK1 | |
| SCHEMBL22000113 | 0.78 | BCHE (0.55) | — | |
| SCHEMBL8811228 | 0.78 | IRAK1 (0.51) | IRAK1IRAK4MAPK1AXLNMT1 | |
| SCHEMBL3340159 | 0.77 | TAAR1 (0.46) | CTSVCTSLCTSBCTSSIRAK1 | |
| SCHEMBL30570078 | 0.77 | MPO (0.45) | CTSVCTSLCTSBCTSSIRAK1 | |
| SCHEMBL30570082 | 0.77 | MPO (0.45) | CTSVCTSLCTSBCTSSIRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |