Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28314002 | 0.84 | NPC1 (0.53) | NPC1MEN1KMT2AACHEHDAC6 | |
| SCHEMBL16445878 | 0.79 | NPC1 (0.49) | NPC1MEN1KMT2AACHEHDAC6 | |
| SCHEMBL9057896 | 0.77 | ALDH1A1 (0.60) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL5242625 | 0.77 | RAB9A (0.61) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL13978684 | 0.76 | MAOB (0.53) | NPC1MEN1KMT2AACHEHDAC6 | |
| SCHEMBL1441804 | 0.73 | PDE10A (0.43) | NPC1MEN1KMT2AACHEHDAC6 | |
| SCHEMBL4844181 | 0.73 | RAB9A (0.76) | NPC1ACHEHDAC6PTPN1PPARG | |
| SCHEMBL30573375 | 0.72 | RAB9A (0.81) | NPC1MEN1KMT2AACHEHDAC6 | |
| SCHEMBL7030328 | 0.72 | RAB9A (0.81) | NPC1MEN1KMT2AACHEHDAC6 | |
| SCHEMBL29184856 | 0.72 | KCNA3 (0.48) | NPC1MEN1KMT2AACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996012718-A1 | NOUVELLES 2-[1-(φ-PHENOXYALCOYLPIPERIDIN-4-YL)AMINOMETHYLENE]-2H-BENZOFURAN-3-ONES SUBSTITUEES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | disclosed |