Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790826 | 0.79 | ALDH1A1 (0.46) | NTSR1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL3589625 | 0.77 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1HTTMITF | |
| SCHEMBL11927945 | 0.77 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HTTMITF | |
| SCHEMBL3594196 | 0.77 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HTTMITF | |
| SCHEMBL30101423 | 0.76 | ALDH1A1 (0.53) | NTSR1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL13039130 | 0.75 | ALDH1A1 (0.43) | NTSR1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL13039127 | 0.75 | ALDH1A1 (0.50) | KMT2AALDH1A1HTTMITFRAB9A | |
| SCHEMBL13039121 | 0.75 | ALDH1A1 (0.43) | NTSR1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL13039128 | 0.75 | ALDH1A1 (0.50) | KMT2AALDH1A1HTTMITFRAB9A | |
| SCHEMBL4881311 | 0.75 | TSHR (0.43) | RAB9ASMN1; SMN2CYP2D6TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996012721-A1 | INDOLE DERIVATIVES USEFUL AS SEROTONERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-02 | — | — | WO | disclosed |