Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 4/20 | 0.89 |
| ▸ | HTR3A | P46098 | 2/20 | 0.89 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.89 |
| ▸ | HTR3B | O95264 | 1/20 | 0.89 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.89 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.89 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.89 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.65 |
| ▸ | HTR1A | P08908 | 4/20 | 0.62 |
| ▸ | HTR1B | P28222 | 2/20 | 0.62 |
| ▸ | HTR1D | P28221 | 2/20 | 0.62 |
| ▸ | HTR7 | P34969 | 3/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 3/20 | 0.57 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.57 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7921830 | 0.98 | ADRB1 (0.86) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL2410870 | 0.94 | ADRB1 (1.00) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL234280 | 0.94 | ADRB1 (1.00) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL1724680 | 0.93 | ADRB1 (0.96) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| Piperazine SCHEMBL8590918 | 0.93 | ADRB1 (0.96) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| Bromide SCHEMBL11070661 | 0.93 | ADRB1 (0.96) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL2302729 | 0.93 | ADRB1 (0.96) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL2881283 | 0.89 | ADRB1 (0.89) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL5237992 | 0.88 | ADRB1 (0.86) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7171062 | 0.88 | ADRB1 (0.86) | ADRB1HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |