Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 12/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TTPA | P49638 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257213 | 0.83 | PSEN1 (0.67) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9063840 | 0.82 | PSEN1 (0.41) | PSEN1TTPA | |
| SCHEMBL10074168 | 0.80 | PSEN1 (0.69) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL1286094 | 0.77 | PTGS1 (0.69) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8994749 | 0.77 | PTGS1 (0.69) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL1286095 | 0.77 | PTGS1 (0.69) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL14948954 | 0.76 | PSEN1 (0.67) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL16215094 | 0.76 | PSEN1 (0.64) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL4592776 | 0.75 | PSEN1 (0.65) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL6597291 | 0.75 | PSEN1 (0.65) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996016957-A1 | 3,4-DIHYDRO-2,5,7,8-TETRAMETHYL-BENZOPYRAN-6-OL DERIVATIVES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-06-06 | — | — | WO | disclosed |