Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2463178 | 0.77 | RXRA (0.47) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL2091407 | 0.74 | RXRA (0.48) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL7096129 | 0.74 | RXRA (0.43) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL7314295 | 0.74 | HDAC6 (0.46) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL9495095 | 0.73 | MEN1 (0.41) | TSHR | |
| SCHEMBL2465113 | 0.73 | RXRA (0.44) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL9059041 | 0.73 | RXRA (0.44) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL7403475 | 0.72 | RXRA (0.43) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL11667482 | 0.71 | RXRA (0.58) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL27666257 | 0.71 | RXRA (0.48) | RXRARXRBRXRGALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996021640-A1 | OPTICALLY ACTIVE AMINOINDANE DERIVATIVES AND PREPARATION THEREOF | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1996-07-18 | — | — | WO | disclosed |