Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1254154 | 0.79 | RXRA (0.47) | RXRARXRBRXRGALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL2864663 | 0.78 | RXRA (0.46) | RXRARXRBRXRGALDH1A1NOX4 | |
| SCHEMBL15466082 | 0.75 | RXRA (0.47) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL22681835 | 0.75 | ALDH1A1 (0.50) | ALDH1A1NPC1POLBRAB9AMAPT | |
| SCHEMBL2091407 | 0.74 | RXRA (0.48) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL9058750 | 0.74 | RXRA (0.45) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL22681798 | 0.73 | RXRA (0.43) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL22681601 | 0.72 | RXRA (0.46) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL22681817 | 0.72 | ALDH1A1 (0.46) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL22744651 | 0.72 | MTNR1A (0.50) | ALDH1A1NPC1RAB9AMAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966435-A4 | AMINOINDAN DERIVATIVES | TEVA PHARMA (IL) | 2003-04-16 | — | — | EP | disclosed |
| EP-0966435-A1 | AMINOINDAN DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998027055-A1 | AMINOINDAN DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1998-06-25 | — | — | WO | disclosed |