Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ACLY | P53396 | 3/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940 | 0.85 | ALDH1A1 (0.55) | TSHRACLYCPT2ALDH1A1CYP2D6 | |
| SCHEMBL10797042 | 0.83 | ALDH1A1 (0.52) | TSHRACLYCPT2ALDH1A1CYP2D6 | |
| SCHEMBL8721139 | 0.83 | ALDH1A1 (0.52) | TSHRACLYCPT2ALDH1A1CYP2D6 | |
| SCHEMBL20973099 | 0.83 | ALDH1A1 (0.52) | TSHRACLYCPT2ALDH1A1CYP2D6 | |
| SCHEMBL11405967 | 0.83 | ALDH1A1 (0.52) | TSHRACLYCPT2ALDH1A1CYP2D6 | |
| Succimer SCHEMBL2511150 | 0.82 | TDP1 (0.50) | TSHRACLYCPT2ALDH1A1CYP2D6 | |
| SCHEMBL330107 | 0.80 | ALDH1A1 (0.50) | TSHRACLYCPT2ALDH1A1CYP2D6 | |
| SCHEMBL2770806 | 0.80 | ALDH1A1 (0.50) | TSHRACLYCPT2ALDH1A1CYP2D6 | |
| Citric Acid SCHEMBL1553183 | 0.79 | ALDH1A1 (0.71) | TSHRACLYCPT2ALDH1A1CYP2D6 | |
| Citric Acid SCHEMBL19205892 | 0.77 | ALDH1A1 (0.68) | TSHRACLYCPT2ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996016327-A1 | FLUORESCENT METAL-CHELATING AMPHIPHILE AND SENSOR | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1996-05-30 | — | — | WO | claimed |