Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TOP1 | P11387 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801047 | 0.95 | LMNA (0.46) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9058925 | 0.91 | LMNA (0.56) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8802048 | 0.88 | LMNA (0.42) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8801042 | 0.87 | LMNA (0.57) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8801646 | 0.86 | THRB (0.41) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8802250 | 0.84 | CNR2 (0.36) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8801018 | 0.82 | LMNA (0.49) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8801026 | 0.81 | LMNA (0.46) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8801932 | 0.81 | LMNA (0.46) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8800505 | 0.81 | LMNA (0.37) | LMNAKMT2AUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002533-A1 | NOVEL 6- AND 6,8-SUBSTITUTED 1-[4-(1H-1,2,4-TRIAZOL-1-YL METHYL) PHENYL] QUINOLONE CARBOXYLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |