SCHEMBL9058982

SCHEMBL9058982

CCCCOC=C(C)C=O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
ATM Q13315 1/20 0.39
TSHR P16473 5/20 0.36
HPGD P15428 1/20 0.36
HCAR2 Q8TDS4 1/20 0.34
CYP3A4 P08684 1/20 0.33
ACHE P22303 6/20 0.32
CES2 O00748 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9058495 0.86
SCHEMBL9058494 0.86
SCHEMBL4429201 0.77
SCHEMBL2716472 0.77
SCHEMBL751024 0.77
SCHEMBL4767183 0.77
SCHEMBL11639406 0.73 ALDH1A1 (0.39) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL11639402 0.73 ALDH1A1 (0.39) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL4437389 0.73 ALDH1A1 (0.39) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL4437386 0.73 ALDH1A1 (0.39) ALDH1A1ATMTSHRHPGDHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996016013-A1 METHOD OF MAKING 2,7-DIMETHYL-2,4,6-OCTATRIENEDIAL, A KEY INTERMEDIATE IN THE COMMERCIAL SYNTHESES OF VARIOUS CAROTENOIDS LOYOLA UNIVERSITY OF CHICAGO (US) 1996-05-30 WO disclosed
US-5471005-A Method of making 2,7-dimethyl-2,4,6-octatrienedial, a key intermediate in the commercial syntheses of various carotenoids LOYOLA UNIVERSITY OF CHICAGO (US) 1995-11-28 US disclosed