SCHEMBL9059332

SCHEMBL9059332

O=C(Cl)C(=O)c1sc(Cl)cc1Cl

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DAO P14920 3/20 0.38
GSK3B P49841 2/20 0.34
F2 P00734 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788357 0.77 DAO (0.50) DAOGSK3B
SCHEMBL5100241 0.76 MAPT (0.40) DAOGSK3B
SCHEMBL3055848 0.65 DAO (0.39) DAOGSK3BF2
SCHEMBL7223067 0.61 DAO (0.34) DAOGSK3B
SCHEMBL3045837 0.61 F10 (0.42) DAOGSK3B
SCHEMBL10861484 0.61 MAPT (0.40) DAOGSK3B
SCHEMBL3425861 0.61 DAO (0.48) DAO
SCHEMBL18701642 0.61 DAO (0.47) DAOGSK3B
SCHEMBL12247521 0.61 IKBKB (0.56) DAOGSK3BF2
SCHEMBL9255277 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996017840-A1 HETEROCYCLYL SUBSTITUTED HYDROXYACETAMIDE DERIVATIVES AS FONGICIDES AGREVO UK LIMITED (GB) 1996-06-13 WO disclosed