Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.40 |
| ▸ | BCKDK | O14874 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100241 | 0.79 | MAPT (0.40) | DAORXFP1ALDH1A1HPGDGSK3B | |
| SCHEMBL18701713 | 0.79 | DAO (0.65) | DAOMCL1BCKDKMAPK1RXFP1 | |
| SCHEMBL18701701 | 0.77 | BCKDK (0.43) | DAOMCL1BCKDKMAPK1RXFP1 | |
| SCHEMBL154245 | 0.77 | GPR35 (0.44) | DAOMCL1BCKDKMAPK1RXFP1 | |
| SCHEMBL20439913 | 0.77 | DAO (0.42) | DAOMCL1BCKDKMAPK1RXFP1 | |
| SCHEMBL6592873 | 0.77 | RXFP1 (0.48) | DAOMCL1BCKDKMAPK1RXFP1 | |
| SCHEMBL3425861 | 0.77 | DAO (0.48) | DAOMCL1BCKDKMAPK1RXFP1 | |
| SCHEMBL9059332 | 0.77 | DAO (0.38) | DAOGSK3B | |
| SCHEMBL18701642 | 0.77 | DAO (0.47) | DAOMCL1BCKDKMAPK1RXFP1 | |
| SCHEMBL28226525 | 0.77 | DAO (0.47) | DAOMCL1BCKDKRXFP1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616466-A2 | PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE | Medichem, S.A. (ES) | 2013-07-24 | — | — | EP | claimed |
| WO-2012035057-A2 | PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE | MEDICHEM S.A. (ES) | 2012-03-22 | — | — | WO | claimed |
| US-20180282605-A1 | METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2018-10-04 | — | — | US | disclosed |
| WO-2017060699-A1 | METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2017-04-13 | — | — | WO | disclosed |
| US-20130253187-A1 | Process for Determining the Suitability for Distribution of a Batch of Thiophene-2-Carboxamide Derivative | MEDICHEM, S.A. (ES) | 2013-09-26 | — | — | US | disclosed |
| EP-2616466-A2 | PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE | Medichem, S.A. (ES) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035057-A2 | PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE | MEDICHEM S.A. (ES) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253187-A1 | Process for Determining the Suitability for Distribution of a Batch of Thiophene-2-Carboxamide Derivative | CYP2C9, CYP3A5, CYP3A43 | DAO 2775/4885MCL1 3321/4885BCKDK 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.