Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425861 | 0.83 | DAO (0.48) | MAPTHPGDKDM4EDAORAB9A | |
| SCHEMBL3055848 | 0.83 | DAO (0.39) | MAPTHPGDKDM4EL3MBTL1DAO | |
| SCHEMBL5100241 | 0.80 | MAPT (0.40) | MAPTHPGDKDM4EL3MBTL1DAO | |
| SCHEMBL26281532 | 0.78 | KMT2A (0.44) | MAPTHPGDKDM4EDAORAB9A | |
| SCHEMBL102004 | 0.77 | ALDH1A1 (0.40) | MAPTHPGDKDM4EDAODHODH | |
| SCHEMBL26281541 | 0.75 | ALOX15 (0.58) | MAPTHPGDKDM4EL3MBTL1DHODH | |
| SCHEMBL5860697 | 0.74 | GSK3B (0.42) | MAPTHPGDKDM4EDAODHODH | |
| SCHEMBL14029306 | 0.74 | KDM4E (0.45) | MAPTHPGDKDM4EDAODHODH | |
| SCHEMBL26241657 | 0.74 | ALDH1A1 (0.38) | MAPTHPGDKDM4EDAODHODH | |
| SCHEMBL14029320 | 0.74 | KDM4E (0.38) | MAPTHPGDKDM4EDAODHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118696034-A | Novel bicyclic compounds as RAD51 inhibitors | 萨提亚疗法股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| US-4590203-A | Derivatives of thiophene-2-carboxylic acid and their pharmaceutically acceptable acid or base addition salts and use in treatment of conditions caused by thromboxane A2 | LAEVOSAN-GESELLSCHAFT M.B.H. & CO. KG (AT) | 1986-05-20 | — | — | US | disclosed |