Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.70 |
| ▸ | MAOB | P27338 | 8/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5543437 | 0.94 | MAOA (0.66) | MAOAMAOBNPC1RAB9AMEN1 | |
| SCHEMBL22181586 | 0.89 | MAOA (0.60) | MAOAMAOBNPC1RAB9AMEN1 | |
| SCHEMBL15426822 | 0.89 | MAOA (0.60) | MAOAMAOBNPC1RAB9AMEN1 | |
| SCHEMBL30724528 | 0.89 | MAOA (0.64) | MAOAMAOBNPC1RAB9AMEN1 | |
| SCHEMBL8716037 | 0.87 | MAOA (0.62) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL8374655 | 0.87 | MAOA (0.62) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL8374654 | 0.87 | MAOA (0.62) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL923674 | 0.86 | MAOA (0.71) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL30791325 | 0.86 | MAOA (0.71) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL1662622 | 0.86 | MAOA (0.75) | MAOAMAOBNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996016054-A1 | CYCLOALKENYL-N-HYDROXYUREAS | PFIZER PHARMACEUTICALS INC. (JP) | 1996-05-30 | — | — | WO | disclosed |