Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059805 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9059319 | 0.92 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9059314 | 0.92 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9059813 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9059862 | 0.75 | POLB (0.37) | ALDH1A1LMNAGAAL3MBTL1KMT2A | |
| SCHEMBL9059323 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1LMNAGAATSHR | |
| SCHEMBL9059454 | 0.73 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9059110 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAGAATSHR | |
| SCHEMBL9059112 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAGAATSHR | |
| SCHEMBL9059822 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |