Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235967 | 0.91 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL5239063 | 0.85 | AVPR2 (0.60) | AVPR2AVPR1A | |
| SCHEMBL5234869 | 0.85 | AVPR2 (0.64) | AVPR2AVPR1AF10 | |
| SCHEMBL9059603 | 0.84 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL9061754 | 0.83 | AVPR2 (0.46) | AVPR2AVPR1A | |
| SCHEMBL5238090 | 0.78 | AVPR2 (0.57) | AVPR2AVPR1ASMN1; SMN2 | |
| SCHEMBL7337329 | 0.77 | AVPR2 (0.46) | AVPR2AVPR1A | |
| SCHEMBL7335574 | 0.77 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL5239585 | 0.76 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL7335693 | 0.76 | AVPR2 (0.53) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022295-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |