SCHEMBL9059958

SCHEMBL9059958

Cc1cc([N+](=O)[O-])c(S(=O)(=O)Oc2cc(C(=O)O)cc(O)c2O)c([N+](=O)[O-])c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 2/20 0.47
PTGS2 P35354 2/20 0.44
GPR35 Q9HC97 2/20 0.44
ABCC3 O15438 1/20 0.42
ABCC4 O15439 1/20 0.42
NR1I2 O75469 1/20 0.42
ABCB11 O95342 1/20 0.42
TTR P02766 1/20 0.42
NR3C1 P04150 1/20 0.42
PGR P06401 1/20 0.42
HTR1A P08908 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
RARB P10826 1/20 0.42
COMT P21964 1/20 0.42
SLC6A2 P23975 1/20 0.42
ADORA1 P30542 1/20 0.42
ADRA1A P35348 1/20 0.42
SLC6A3 Q01959 1/20 0.42
KCNH2 Q12809 1/20 0.42
KLF10 Q13118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9053200 0.82 PTGS2 (0.51) TPMTPTGS2POLBPOLA1ANTXR2
SCHEMBL9058254 0.79 HPGD (0.49) TPMTPOLBCA1CA2ALDH1A1
SCHEMBL9058253 0.79 HPGD (0.49) TPMTPOLBCA1CA2ALDH1A1
SCHEMBL7937565 0.77 PTGS2 (0.51) TPMTPTGS2POLBPOLA1ANTXR2
SCHEMBL9055309 0.76 KMT2A (0.48) PTGS2POLBPOLA1ANTXR2CA12
SCHEMBL9056610 0.75 TPMT (0.41) TPMTPTGS2GPR35TTRPOLB
SCHEMBL9056672 0.74 TSHR (0.33) POLBTSHRCA12CA1CA2
SCHEMBL9052519 0.73 PTGS2 (0.50) TPMTPTGS2TTRPOLBPOLA1
SCHEMBL9056474 0.72 TP53 (0.49) POLBCA1CA2CA5AKDM4E
SCHEMBL9056482 0.72 TP53 (0.49) POLBCA1CA2CA5AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996008483-A1 GALLIC ACID DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS ROUSSEL UCLAF (FR) 1996-03-21 WO disclosed