SCHEMBL9059971

SCHEMBL9059971

CCCCN(C)C(=N)N(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
DNM1 Q05193 3/20 0.35
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA9 Q16790 3/20 0.33
EPHX2 P34913 3/20 0.33
ALDH2 P05091 1/20 0.33
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP8 P22894 1/20 0.31
CA2 P00918 1/20 0.31
SPHK2 Q9NRA0 1/20 0.31
SPHK1 Q9NYA1 1/20 0.31
ANPEP P15144 1/20 0.31
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9059964 1.00 ALDH1A1 (0.36) ALDH1A1DNM1CA12CA1CA9
SCHEMBL15182726 0.84 CA12 (0.31) CA12CA1CA9CA2
SCHEMBL23498294 0.81 CA12 (0.42) ALDH1A1DNM1CA12CA1CA9
SCHEMBL23458164 0.80 CA12 (0.43) ALDH1A1DNM1CA12CA1CA9
SCHEMBL24146695 0.78 DNM1 (0.44) DNM1CA12CA1CA9EPHX2
SCHEMBL1706032 0.78 EPHX2 (0.30) DNM1EPHX2NOS3NOS1NOS2
SCHEMBL9482900 0.77
SCHEMBL23458211 0.76 CA12 (0.40) ALDH1A1DNM1CA12CA1CA9
SCHEMBL23498115 0.76 CA12 (0.47) ALDH1A1DNM1CA12CA1CA9
SCHEMBL28938998 0.76 CA12 (0.42) ALDH1A1CA12CA1CA9ALDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4073130-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2023-12-27 EP claimed
US-20230028786-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2023-01-26 US claimed
CN-114729079-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2023-01-24 CN claimed
EP-4073130-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2022-10-19 EP claimed
CN-114729079-A Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2022-07-08 CN claimed
WO-2021115829-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2021-06-17 WO claimed
EP-0385038-B1 ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM The Boots Company PLC (GB) 1993-06-02 EP claimed
EP-0385038-A1 Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them The Boots Company PLC (GB) 1990-09-05 EP claimed
US-12012476-B2 Catalyst for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2024-06-18 US disclosed
EP-4073130-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2023-12-27 EP disclosed
US-20230028786-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2023-01-26 US disclosed
CN-114729079-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2023-01-24 CN disclosed
US-20230002516-A1 CATALYST FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2023-01-05 US disclosed
EP-4073130-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2022-10-19 EP disclosed
WO-2021110563-A1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2021-06-10 WO disclosed
WO-1996017612-A1 USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA KNOLL AKTIENGESELLSCHAFT (DE) 1996-06-13 WO disclosed
US-5373008-A Phenylamidine and phenylguanidine derivatives and their use as anti-diabetic agents THE BOOTS COMPANT PLC. (GB) 1994-12-13 US disclosed
US-5223498-A Hypoglycemic agents THE BOOTS COMPANY PLC (GB) 1993-06-29 US disclosed
EP-0385038-B1 ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM The Boots Company PLC (GB) 1993-06-02 EP disclosed
EP-0385038-A1 Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them The Boots Company PLC (GB) 1990-09-05 EP disclosed