Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060278 | 0.83 | KDM4E (0.48) | MAPTKDM4ETP53CYP3A4ALOX15 | |
| SCHEMBL9063470 | 0.80 | — | — | |
| SCHEMBL8962453 | 0.77 | MAPT (0.42) | MAPTKDM4ETP53CYP3A4ALOX15 | |
| SCHEMBL8856463 | 0.70 | KDM4E (0.63) | MAPTKDM4ETP53CYP3A4ALOX15 | |
| SCHEMBL9498075 | 0.69 | KDM4E (0.58) | MAPTKDM4ETP53CYP3A4ALOX15 | |
| SCHEMBL9498087 | 0.69 | KDM4E (0.58) | MAPTKDM4ETP53CYP3A4ALOX15 | |
| SCHEMBL7572036 | 0.69 | KDM4E (0.50) | MAPTKDM4ETP53CYP3A4ALOX15 | |
| SCHEMBL7570251 | 0.69 | KDM4E (0.52) | MAPTKDM4ETP53CYP3A4ALOX15 | |
| SCHEMBL8962452 | 0.68 | KDM4E (0.48) | MAPTKDM4ETP53CYP3A4ALOX15 | |
| SCHEMBL13771852 | 0.67 | KDM4E (0.68) | MAPTKDM4ETP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019446-A1 | β-CARBOXY SULFONAMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | claimed |