Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | TTPA | P49638 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058170 | 0.94 | MAPT (0.47) | MAPTMEN1KMT2ATDP1ALOX5 | |
| SCHEMBL3522249 | 0.85 | CYP4F2 (0.53) | MAPTMEN1KMT2AALOX5PTGS1 | |
| SCHEMBL9467233 | 0.82 | ALOX5 (0.55) | MAPTMEN1KMT2AALOX5PTGS1 | |
| SCHEMBL9075511 | 0.79 | NR1I2 (0.51) | MAPTMEN1KMT2ATDP1ALOX5 | |
| SCHEMBL15851242 | 0.79 | MAPT (0.55) | MAPTMEN1KMT2ATDP1ALOX5 | |
| SCHEMBL9690390 | 0.78 | ALOX5 (0.50) | MAPTMEN1KMT2ATDP1ALOX5 | |
| SCHEMBL8616499 | 0.78 | MAPT (0.53) | MAPTMEN1KMT2ATDP1ALOX5 | |
| SCHEMBL8003203 | 0.77 | MAPT (0.64) | MAPTMEN1KMT2ATDP1ALOX5 | |
| SCHEMBL8122179 | 0.77 | PSEN1 (0.40) | MAPTMEN1KMT2ATDP1ALOX5 | |
| SCHEMBL8131430 | 0.77 | PSEN1 (0.45) | MAPTMEN1KMT2ATDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996016957-A1 | 3,4-DIHYDRO-2,5,7,8-TETRAMETHYL-BENZOPYRAN-6-OL DERIVATIVES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-06-06 | — | — | WO | disclosed |