Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | TTPA | P49638 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986932 | 0.92 | MAPT (0.61) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL7492850 | 0.89 | MAPT (0.59) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL9632107 | 0.88 | MAPT (0.60) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL8619704 | 0.85 | MAPT (0.57) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL7492546 | 0.83 | MAPT (0.53) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL10640259 | 0.82 | PPARG (0.64) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL5674716 | 0.82 | MEN1 (0.61) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL3146466 | 0.82 | MEN1 (0.61) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL13256846 | 0.82 | MEN1 (0.61) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL3287975 | 0.82 | MEN1 (0.61) | MAPTMEN1KMT2ATDP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238757-A1 | NOVEL TREATMENT | SMITHKLINE BEECHAM P.L.C. | 2007-10-11 | — | — | US | disclosed |
| US-20070238757-A1 | NOVEL TREATMENT | SMITHKLINE BEECHAM P.L.C. | 2007-10-11 | — | — | US | disclosed |
| WO-2000010994-A1 | PROCESS FOR THE PREPARATION OF 2-(ARYLOXYMETHYL)-2,5,7,8-TETRAMETHYLCHROMAN-6-OLS | SANKYO COMPANY, LIMITED (JP) | 2000-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238757-A1 | NOVEL TREATMENT | PPARG, PPARA, NLN | MAPT 330/4885MEN1 4848/4885KMT2A 3312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.