Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258172 | 0.79 | KCNN4 (0.52) | ALDH1A1ESR1ESR2CYP3A4KCNN4 | |
| SCHEMBL3818905 | 0.79 | KCNN4 (0.52) | ALDH1A1ESR1ESR2CYP3A4KCNN4 | |
| SCHEMBL4145653 | 0.79 | KCNN4 (0.52) | ALDH1A1ESR1ESR2CYP3A4KCNN4 | |
| Hydrochloric Acid SCHEMBL6404061 | 0.78 | ALDH1A1 (0.46) | ALDH1A1ESR1ESR2CYP3A4KCNN4 | |
| SCHEMBL28555564 | 0.75 | KCNN4 (0.48) | ALDH1A1ESR1ESR2CYP3A4KCNN4 | |
| SCHEMBL27699877 | 0.75 | KCNN4 (0.48) | ALDH1A1ESR1ESR2CYP3A4KCNN4 | |
| SCHEMBL13539518 | 0.75 | KCNN4 (0.48) | ALDH1A1ESR1ESR2CYP3A4KCNN4 | |
| SCHEMBL1169117 | 0.75 | KCNN4 (0.48) | ALDH1A1ESR1ESR2CYP3A4KCNN4 | |
| SCHEMBL27598729 | 0.75 | KCNN4 (0.42) | ALDH1A1ESR1ESR2CYP3A4KCNN4 | |
| SCHEMBL28512430 | 0.73 | KCNN4 (0.46) | ALDH1A1ESR1ESR2CYP3A4KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305929-B1 | Membranes with bound oligonucleotides and peptides | MILLIPORE CORP (US) | 1996-04-10 | — | — | EP | disclosed |
| US-4923901-A | Membranes with bound oligonucleotides and peptides | MILLIPORE CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0305929-A2 | Membranes with bound oligonucleotides and peptides | MILLIPORE CORPORATION (US) | 1989-03-08 | — | — | EP | disclosed |