Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3818905 | 1.00 | KCNN4 (0.52) | KCNN4MAPTKMT2AALDH1A1TAAR1 | |
| SCHEMBL1258172 | 1.00 | KCNN4 (0.52) | KCNN4MAPTKMT2AALDH1A1TAAR1 | |
| SCHEMBL6360840 | 0.82 | KCNN4 (0.58) | KCNN4MAPTKMT2AALDH1A1TAAR1 | |
| SCHEMBL27699877 | 0.79 | KCNN4 (0.48) | KCNN4MAPTKMT2AALDH1A1TAAR1 | |
| SCHEMBL9060296 | 0.79 | ALDH1A1 (0.48) | KCNN4MAPTKMT2AALDH1A1TAAR1 | |
| SCHEMBL13539518 | 0.79 | KCNN4 (0.48) | KCNN4MAPTKMT2AALDH1A1TAAR1 | |
| SCHEMBL1169117 | 0.79 | KCNN4 (0.48) | KCNN4MAPTKMT2AALDH1A1TAAR1 | |
| SCHEMBL28512430 | 0.77 | KCNN4 (0.46) | KCNN4MAPTKMT2AALDH1A1TAAR1 | |
| Hydrochloric Acid SCHEMBL6404061 | 0.77 | ALDH1A1 (0.46) | KCNN4MAPTKMT2AALDH1A1TAAR1 | |
| SCHEMBL28029040 | 0.77 | KCNN4 (0.46) | KCNN4MAPTKMT2AALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110198928-B | Benzyloxy-pyridinyl-cyclopropanecarboxylic acid, pharmaceutical compositions and uses thereof | 勃林格殷格翰国际有限公司 | 2023-08-29 | — | — | CN | disclosed |
| US-10800778-B2 | Beta-lactamase inhibitor compounds | ENTASIS THERAPEUTICS LIMITED (GB) | 2020-10-13 | — | — | US | disclosed |
| EP-3663308-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND | Samsung Electronics Co., Ltd. (KR) | 2020-06-10 | — | — | EP | disclosed |
| US-20190202832-A1 | BETA-LACTAMASE INHIBITOR COMPOUNDS | ENTASIS THERAPEUTICS LIMITED (GB) | 2019-07-04 | — | — | US | disclosed |
| CN-105177070-A | Method for yeast production of (S)-aminophenyl ethanol | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-12-23 | — | — | CN | disclosed |
| CN-105177070-A | Method for yeast production of (S)-aminophenyl ethanol | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-12-23 | — | — | CN | disclosed |
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLANT ANDREW | 2009-01-08 | — | — | US | disclosed |
| US-7419936-B2 | Optically active 2,5-bisaryl-Δ1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2008-09-02 | — | — | US | disclosed |
| CN-101035537-A | Compositions and methods for treating ocular diseases | MERCK & CO INC (US) | 2007-09-12 | — | — | CN | disclosed |
| CN-1976927-A | Quinoline thiazolinone compound | HOFFMANN LA ROCHE (CH) | 2007-06-06 | — | — | CN | disclosed |
| EP-1076646-B1 | METHOD FOR STEREOCHEMICALLY CONTROLLED PRODUCTION OF ISOMERICALLY PURE HIGHLY SUBSTITUTED AZACYCLIC COMPOUNDS | SOLVAY PHARM GMBH (DE) | 2004-08-04 | — | — | EP | disclosed |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2004-03-25 | — | — | US | disclosed |
| US-20030220517-A1 | Method for producing ketocarboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2003-11-27 | — | — | US | disclosed |
| EP-1322587-A1 | METHOD FOR PRODUCING KETOCARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2003-07-02 | — | — | EP | disclosed |
| EP-1322607-A1 | OPTICALLY ACTIVE 2,5-BISARYL-DELTA1-PYRROLINES AND THEIR USE AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024622-A1 | METHOD FOR PRODUCING KETOCARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2002-03-28 | — | — | WO | disclosed |
| WO-2002024643-A1 | OPTICALLY ACTIVE 2,5-BISARYL-DELTA1-PYRROLINES AND THEIR USE AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2002-03-28 | — | — | WO | disclosed |
| CN-1291978-A | Meta-azacyclic amino benzoic acid compound and derivatives thereof being integrin antagonists | SEARLE & CO (US) | 2001-04-18 | — | — | CN | disclosed |
| EP-1076646-A1 | METHOD FOR STEREOCHEMICALLY CONTROLLED PRODUCTION OF ISOMERICALLY PURE HIGHLY SUBSTITUTED AZACYCLIC COMPOUNDS | Solvay Pharmaceuticals GmbH (DE) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999058500-A1 | METHOD FOR STEREOCHEMICALLY CONTROLLED PRODUCTION OF ISOMERICALLY PURE HIGHLY SUBSTITUTED AZACYCLIC COMPOUNDS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1999-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190202832-A1 | BETA-LACTAMASE INHIBITOR COMPOUNDS | LCT, MGAM, MRPL21 | KCNN4 3126/4885MAPT 3891/4885KMT2A 1573/4885 |
| US-20030220517-A1 | Method for producing ketocarboxylic acid derivatives | CYP2F1, HK1, FBP1 | KCNN4 725/4885MAPT 4405/4885KMT2A 2252/4885 |
| US-10800778-B2 | Beta-lactamase inhibitor compounds | LCT, MGAM, MRPL21 | KCNN4 3126/4885MAPT 3891/4885KMT2A 1573/4885 |
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLD1, RPS3A, AMY1A | KCNN4 3534/4885MAPT 2959/4885KMT2A 3981/4885 |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | DDT, CRY1, PLD1 | KCNN4 2099/4885MAPT 3257/4885KMT2A 3858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.