Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29236231 | 0.88 | ALDH1A1 (0.59) | ALDH1A1TDP1HPRT1RAB9APOLB | |
| SCHEMBL6011656 | 0.87 | ALDH1A1 (0.47) | ALDH1A1TDP1HPRT1RAB9APOLB | |
| SCHEMBL27458439 | 0.87 | ALDH1A1 (0.47) | ALDH1A1TDP1HPRT1RAB9APOLB | |
| SCHEMBL153658 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TDP1HPRT1RAB9APOLB | |
| SCHEMBL1556277 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TDP1HPRT1RAB9APOLB | |
| SCHEMBL27475137 | 0.84 | HPRT1 (0.50) | ALDH1A1TDP1HPRT1RAB9APOLB | |
| SCHEMBL8863198 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TDP1HPRT1RAB9APOLB | |
| SCHEMBL3700629 | 0.84 | MEN1 (0.47) | ALDH1A1TDP1RAB9APOLBLMNA | |
| SCHEMBL29209663 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TDP1RAB9APOLBLMNA | |
| SCHEMBL27832802 | 0.79 | MEN1 (0.53) | ALDH1A1TDP1POLBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556730-A | Charge injection barrier for positive charging organic photoconductor | HEWLETT-PACKARD COMPANY (US) | 1996-09-17 | — | — | US | disclosed |
| US-5476604-A | Crosslinked binder of polyvinyl alcohol | HEWLETT-PACKARD COMPANY (US) | 1995-12-19 | — | — | US | disclosed |
| EP-0667562-A2 | Charge injection barrier for positive charging organic photoconductor | Hewlett-Packard Company (US) | 1995-08-16 | — | — | EP | disclosed |