Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611508 | 1.00 | GPR84 (0.51) | GPR84HTR2AFFAR1HTR2CHTR2B | |
| SCHEMBL7316265 | 0.82 | GPR84 (0.51) | GPR84HTR2AFFAR1HTR2CHTR2B | |
| SCHEMBL6157434 | 0.81 | GPR84 (0.55) | GPR84HTR2AFFAR1HTR2CHTR2B | |
| SCHEMBL3751138 | 0.81 | GPR84 (0.56) | GPR84HTR2AFFAR1HTR2CHTR2B | |
| SCHEMBL14041262 | 0.81 | GPR84 (0.56) | GPR84HTR2AFFAR1HTR2CHTR2B | |
| SCHEMBL13267637 | 0.81 | GPR84 (0.56) | GPR84HTR2AFFAR1HTR2CHTR2B | |
| SCHEMBL6888701 | 0.79 | GPR84 (0.56) | GPR84HTR2AFFAR1HTR2CHTR2B | |
| SCHEMBL11374722 | 0.79 | GPR84 (0.51) | GPR84HTR2AFFAR1HTR2CHTR2B | |
| SCHEMBL2995918 | 0.78 | HTR2A (0.51) | GPR84HTR2AFFAR1HTR2CHTR2B | |
| SCHEMBL11884580 | 0.77 | AHR (0.43) | ADRB1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8157471-A | — | — | None | — | — | JP | disclosed |
| JP-H08157471-A | 3-(BENZENESULFONAMIDOALKYL)INDOLE DERIVATIVE | TERUMO CORP | 1996-06-18 | — | — | JP | disclosed |