Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611508 | 0.82 | GPR84 (0.51) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL9060404 | 0.82 | GPR84 (0.51) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL11805598 | 0.81 | GPR84 (0.55) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL6668005 | 0.81 | GPR84 (0.59) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL27640048 | 0.80 | GPR84 (0.54) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL29951612 | 0.79 | GPR84 (0.61) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL13767828 | 0.79 | GPR84 (0.61) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL1333393 | 0.79 | GPR84 (0.51) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL10069423 | 0.77 | GPR84 (0.46) | GPR84HTR2AMEN1KMT2ASLC6A4 | |
| SCHEMBL1296387 | 0.76 | GPR84 (0.53) | GPR84FFAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719199-A | VASORPRESSIN ANTAGONIST | SMITHKLINE BECKMAN CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719199-A | VASORPRESSIN ANTAGONIST | SMITHKLINE BECKMAN CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| US-4684716-A | VASOPRESSIN ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1987-08-04 | — | — | US | disclosed |
| US-4684716-A | VASOPRESSIN ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1987-08-04 | — | — | US | disclosed |
| US-4597901-A | POLYPEPTIDES, DIURESIS | SMITHKLINE BECKMAN CORPORATION (US) | 1986-07-01 | — | — | US | disclosed |
| US-4597901-A | POLYPEPTIDES, DIURESIS | SMITHKLINE BECKMAN CORPORATION (US) | 1986-07-01 | — | — | US | disclosed |