Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84800 | 0.85 | HSD11B1 (0.43) | HSD11B1GBA1KDM4EMAPTALDH1A1 | |
| SCHEMBL21664675 | 0.83 | HSD11B1 (0.42) | HSD11B1GBA1KDM4EMAPTALDH1A1 | |
| SCHEMBL6057032 | 0.82 | — | — | |
| SCHEMBL8149011 | 0.82 | HSD11B1 (0.47) | HSD11B1GBA1KDM4EALDH1A1MAP4K4 | |
| SCHEMBL4893194 | 0.82 | HSD11B1 (0.47) | HSD11B1GBA1KDM4EALDH1A1MAP4K4 | |
| SCHEMBL12047310 | 0.80 | — | — | |
| SCHEMBL20325073 | 0.79 | HSD11B1 (0.40) | HSD11B1GBA1KDM4EMAPTALDH1A1 | |
| SCHEMBL20843598 | 0.79 | KDM4E (0.31) | KDM4EMAPTALDH1A1 | |
| SCHEMBL2916819 | 0.77 | CHKA (0.43) | HSD11B1KDM4EMEN1KMT2A | |
| SCHEMBL21025901 | 0.77 | ALDH1A1 (0.47) | HSD11B1KDM4EMAPTALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115418632-B | High-speed high-ductility chemical copper suitable for horizontal line equipment and preparation method thereof | 深圳市富利特科技有限公司 | 2023-11-17 | — | — | CN | claimed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| CN-115418632-B | High-speed high-ductility chemical copper suitable for horizontal line equipment and preparation method thereof | 深圳市富利特科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| US-20210249595-A1 | CONDUCTIVE BRIDGE MEMORY DEVICE, MANUFACTURING METHOD THEREOF, AND SWITCHING ELEMENT | NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) | 2021-08-12 | — | — | US | disclosed |
| EP-3809456-A1 | CONDUCTIVE-BRIDGE MEMORY DEVICE AND PRODUCTION METHOD THEREFOR, AND SWITCH ELEMENT | National University Corporation Tottori University (JP) | 2021-04-21 | — | — | EP | disclosed |
| US-8071080-B2 | May be imidazolium, pyrazolium, pyridinium, pyrimidinium or tetraalkylphosphonium salts; washing (cleaning) and/or conditioning keratin materials, and especially the hair. | L'OREAL (FR) | 2011-12-06 | — | — | US | disclosed |
| US-8071080-B2 | May be imidazolium, pyrazolium, pyridinium, pyrimidinium or tetraalkylphosphonium salts; washing (cleaning) and/or conditioning keratin materials, and especially the hair. | L'OREAL (FR) | 2011-12-06 | — | — | US | disclosed |
| EP-1362572-B1 | Use of at least one particular organic salt for cleansing and/or conditioning keratinous materials, use of a particular organic salt as conditioning agent for said materials and process for cosmetic treatment | OREAL (FR) | 2008-04-16 | — | — | EP | disclosed |
| CN-1037346-C | Therapeutic agents | BOOTS CO LTD (GB) | 1998-02-11 | — | — | CN | disclosed |
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |
| US-5373008-A | Phenylamidine and phenylguanidine derivatives and their use as anti-diabetic agents | THE BOOTS COMPANT PLC. (GB) | 1994-12-13 | — | — | US | disclosed |
| US-5223498-A | Hypoglycemic agents | THE BOOTS COMPANY PLC (GB) | 1993-06-29 | — | — | US | disclosed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | disclosed |
| CN-1057648-A | Therapeutical agent | BOOTS CO PLC (GB) | 1992-01-08 | — | — | CN | disclosed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | disclosed |