Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 15/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3916599 | 0.84 | APP (0.63) | APPMAOBIDO1MAOA | |
| SCHEMBL27521276 | 0.84 | MAOB (0.77) | MAOBIDO1NR4A2PARP10MAOA | |
| SCHEMBL30674750 | 0.84 | APP (0.63) | APPMAOBIDO1MAOA | |
| SCHEMBL5038027 | 0.83 | MAOB (0.71) | APPMAOBIDO1NR4A2PARP10 | |
| SCHEMBL5708187 | 0.82 | APP (0.61) | APPMAOBIDO1MAOA | |
| SCHEMBL5708184 | 0.81 | APP (0.59) | APPMAOBIDO1MAOA | |
| SCHEMBL16808972 | 0.79 | MAOB (0.63) | MAOBIDO1NR4A2MAOA | |
| SCHEMBL21480409 | 0.79 | MAOB (0.71) | APPMAOBNR4A2PARP10MAOA | |
| SCHEMBL8306880 | 0.79 | MAOB (0.71) | MAOBPARP10MAOA | |
| SCHEMBL9440467 | 0.78 | APP (1.00) | APPMAOBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996016054-A1 | CYCLOALKENYL-N-HYDROXYUREAS | PFIZER PHARMACEUTICALS INC. (JP) | 1996-05-30 | — | — | WO | disclosed |