SCHEMBL9060697

SCHEMBL9060697

O=C(Cl)OCCOc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.60
LMNA P02545 4/20 0.58
MAPK1 P28482 2/20 0.58
CYP1A2 P05177 2/20 0.58
PGR P06401 2/20 0.58
SLC6A2 P23975 2/20 0.58
CYP2C19 P33261 2/20 0.58
ALDH1A1 P00352 1/20 0.58
CYP2D6 P10635 1/20 0.58
PDE4A P27815 1/20 0.58
HRH1 P35367 1/20 0.58
HTT P42858 1/20 0.58
SLC6A3 Q01959 1/20 0.58
PDE4D Q08499 1/20 0.58
GAA P10253 2/20 0.54
MEN1 O00255 1/20 0.54
USP2 O75604 1/20 0.54
KMT2A Q03164 1/20 0.54
KEAP1 Q14145 1/20 0.54
NFE2L2 Q16236 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12743862 0.90 LMNA (0.69) HPGDLMNAMAPK1CYP1A2PGR
SCHEMBL7157287 0.89 HPGD (0.63) HPGDLMNAMAPK1CYP1A2PGR
SCHEMBL9717091 0.88 HPGD (0.62) HPGDLMNAMAPK1CYP1A2PGR
SCHEMBL5028940 0.88 LMNA (0.66) HPGDLMNAMAPK1CYP1A2PGR
SCHEMBL31264192 0.87 HPGD (0.64) HPGDLMNAMAPK1CYP1A2PGR
SCHEMBL7754349 0.87 HPGD (0.64) HPGDLMNAMAPK1CYP1A2PGR
SCHEMBL241583 0.87 HPGD (0.64) HPGDLMNAMAPK1CYP1A2PGR
SCHEMBL9717125 0.87 HPGD (0.60) HPGDLMNAMAPK1CYP1A2PGR
SCHEMBL9717126 0.87 HPGD (0.60) HPGDLMNAMAPK1CYP1A2PGR
SCHEMBL545524 0.86 HPGD (0.68) HPGDLMNAMAPK1CYP1A2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0472819-B1 Polymeric peroxides derived from hydroxy-hydroperoxides and dihydroxy-dialkyl peroxides and their use ATOCHEM NORTH AMERICA ELF (US) 1996-08-21 EP disclosed
US-5457162-A Catalyst for addition polymerization, curing and crosslinking ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-10-10 US disclosed
US-5399630-A Process for curing polymers using amino or hydrazino peroxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-03-21 US disclosed
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
EP-0355733-B1 Amino or hydrazino peroxides, derivatives and their uses ATOCHEM NORTH AMERICA (US) 1995-02-08 EP disclosed
US-5360867-A Reactive with maleic acid or maleic anhydride polymer ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-11-01 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed
US-5272219-A Process for preparing amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-12-21 US disclosed
EP-0303283-B1 2-HYDROXYBENZOPHENONE HYDRAZIDES AND DERIVATIVES THEREOF ATOCHEM NORTH AMERICA, INC. (US) 1993-02-03 EP disclosed
US-5162405-A Single-functional and mixtures of multi-functional oligomeric performance additive compositions and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-11-10 US disclosed
EP-0472819-A2 Polymeric peroxides derived from hydroxy-hydroperoxides and dihydroxy-dialkyl peroxides and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-03-04 EP disclosed
US-5041545-A 2-hydroxybenzophenone hydrazides and derivatives thereof ATOCHEM NORTH AMERICA, INC. (US) 1991-08-20 US disclosed
US-5039754-A Block copolymer;compatibilizing polymer blends and alloy ATOCHEM NORTH AMERICA, INC. (US) 1991-08-13 US disclosed
US-5013777-A Benzosulfonic acids as end groups of engineering thermoplastic resins; fireproofing; oxidation and UV resistances; photostabilizers ATOCHEM NORTH AMERICA, INC. (US) 1991-05-07 US disclosed
US-4956416-A CURING UNSATURATED POLYESTERS; ADDITION POLYMERIZATION CATALYSTS; COAVALENTLY BOUND PERFORMANCE ADDITIVE FUNCTIONS; GRAFT AND BLOCK POLYMERS; SELF-CURING ATOCHEM NORTH AMERICA, INC. (US) 1990-09-11 US disclosed
EP-0355733-A1 Amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1990-02-28 EP disclosed
EP-0332761-A2 Single-functional and mixtures of multifunctional oligomeric performance additive compositions, and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-09-20 EP disclosed
EP-0303283-A2 2-Hydroxybenzophenone hydrazides and derivatives thereof ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed