Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | RARB | P10826 | 9/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062058 | 0.99 | RARB (0.49) | PPARARARBHSD11B1PTPN1RARA | |
| SCHEMBL9061533 | 0.99 | RARB (0.49) | PPARARARBHSD11B1PTPN1RARA | |
| SCHEMBL9061670 | 0.99 | RARB (0.49) | PPARARARBHSD11B1PTPN1RARA | |
| SCHEMBL9061547 | 0.99 | RARB (0.49) | PPARARARBHSD11B1PTPN1RARA | |
| SCHEMBL9061026 | 0.99 | RARB (0.49) | PPARARARBHSD11B1PTPN1RARA | |
| SCHEMBL9060992 | 0.96 | HSD11B1 (0.44) | PPARARARBHSD11B1PTPN1PPARG | |
| SCHEMBL8377179 | 0.93 | PPARA (0.47) | PPARARARBHSD11B1PTPN1PPARG | |
| SCHEMBL9061315 | 0.91 | PPARA (0.44) | PPARAPPARG | |
| SCHEMBL9060761 | 0.88 | PPARA (0.44) | PPARARARBPPARG | |
| SCHEMBL9061034 | 0.87 | PPARA (0.46) | PPARARARBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5389292-A | Liquid crystalline media having positive dielctric anisotropy, chemical, heat and radiation resistance, used as electro-optical displaying | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0381728-B1 | DIFLUOROMETHYL COMPOUNDS | MERCK PATENT GMBH (DE) | 1993-12-08 | — | — | EP | disclosed |